发明授权
EP1603566B1 USE OF ISOQUINOLINE DERIVATIVES FOR TREATING CANCER AND MAP KINASE RELATED DISEASES
有权
异喹啉衍生物对癌症的治疗和疾病相关的地图激酶USE
- 专利标题： USE OF ISOQUINOLINE DERIVATIVES FOR TREATING CANCER AND MAP KINASE RELATED DISEASES
- 专利标题（中）： 异喹啉衍生物对癌症的治疗和疾病相关的地图激酶USE
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申请号： EP04718960.0申请日： 2004-03-10
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公开(公告)号： EP1603566B1公开(公告)日： 2009-01-21
- 发明人: BATT, David, Bryant , BOLD, Guido , KIM, Sunkyu , RAMSEY, Timothy, Michael , SABIO, Michael, Lloyd
- 申请人： NOVARTIS AG
- 申请人地址： Lichtstrasse 35 4056 Basel CH
- 专利权人： NOVARTIS AG
- 当前专利权人： NOVARTIS AG
- 当前专利权人地址： Lichtstrasse 35 4056 Basel CH
- 代理机构： de Weerd, Petrus G.W.
- 优先权： US453624P 20030311
- 国际公布： WO2004080464 20040923
- 主分类号： A61K31/4725
- IPC分类号： A61K31/4725 ; A61P35/00
摘要：
This invention relates to the treatment of a disease that is characterized by an aberrant MAP kinase signaling pathway by administering a compound of the formula (I) wherein the variable substituents are defined herein, to a patient in need of such treatment. The inventive method is especially useful for the treatment of cancers that have a mutated RAF kinase, especially melanoma.
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