发明公开
EP1604041A1 SCREENING ASSAYS FOR TARGETS AND DRUGS USEFUL IN TREATMENT AND PREVENTION OF LIPID METABOLISM DISORDERS
审中-公开
筛选试验药物和目标，适用于治疗和预防脂肪代谢问题的
- 专利标题： SCREENING ASSAYS FOR TARGETS AND DRUGS USEFUL IN TREATMENT AND PREVENTION OF LIPID METABOLISM DISORDERS
- 专利标题（中）： 筛选试验药物和目标，适用于治疗和预防脂肪代谢问题的
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申请号： EP04720559.6申请日： 2004-03-15
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公开(公告)号： EP1604041A1公开(公告)日： 2005-12-14
- 发明人: HEKIMI, Siegfried , Shibata, Yukimasa , BRANICKY, Robyn
- 申请人： McGill University
- 申请人地址： 845 Sherbrooke Street West Montreal,Québec H3A 1B1 CA
- 专利权人： McGill University
- 当前专利权人： McGill University
- 当前专利权人地址： 845 Sherbrooke Street West Montreal,Québec H3A 1B1 CA
- 代理机构： Desaix, Anne
- 优先权： US454925P 20030314
- 国际公布： WO2004081231 20040923
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68 ; G01N33/92 ; C12Q1/26 ; C07K14/435
摘要：
The invention relates to the use of C. elegans as a model for identifying genes that are involved in lipid or lipoprotein metabolism and which can serve as drug targets. The invention also provides a system for screening drugs useful in the treatment and prevention of diseases associated with undesirable or abnormal levels of lipids (e.g., cholesterol) or lipoproteins (e.g., LDL), such as cardiovascular disorders and dyslipidemia.
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