发明公开
- 专利标题： BI-CYCLIC PYRIMIDINE INHIBITORS OF TGF BETA
- 专利标题（中）： TGF-β的双环嘧啶抑制剂
-
申请号： EP04758392.7申请日： 2004-03-26
-
公开(公告)号： EP1608631A2公开(公告)日： 2005-12-28
- 发明人: DUGAR, Sundeep , CHAKRAVARTY, Sarvajit , CONTE, Aurelia , AXON, Jonathan , MCENROE, Glenn
- 申请人： SCIOS INC.
- 申请人地址： 6500 Paseo Padre Parkway Fremont, CA 94555 US
- 专利权人： SCIOS INC.
- 当前专利权人： SCIOS INC.
- 当前专利权人地址： 6500 Paseo Padre Parkway Fremont, CA 94555 US
- 代理机构： Fisher, Adrian John
- 优先权： US458982P 20030328
- 国际公布： WO2004087056 20041014
- 主分类号： C07D239/70
- IPC分类号： C07D239/70 ; C07D487/04 ; C07D491/048 ; C07D495/04
摘要：
Compounds in which a pyrimidine nucleus is bridged at the (5) and (6) position and are further substituted at positions (2) and (4) with substituents comprising aromatic moieties are useful in treating subjects with conditions ameliorated by inhibition of TGFβ activity.
信息查询
