发明授权
EP1611104B1 TETRAHYDROISOQUINOLYL ACETAMIDE DERIVATIVES FOR USE AS OREXIN RECEPTOR ANTAGONISTS
有权
TETRAHYDROISOCHINOLYLACETAMIDDERIVATE FOR USE作为食欲素受体拮抗剂
- 专利标题: TETRAHYDROISOQUINOLYL ACETAMIDE DERIVATIVES FOR USE AS OREXIN RECEPTOR ANTAGONISTS
- 专利标题(中): TETRAHYDROISOCHINOLYLACETAMIDDERIVATE FOR USE作为食欲素受体拮抗剂
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申请号: EP04722563.6申请日: 2004-03-23
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公开(公告)号: EP1611104B1公开(公告)日: 2009-07-01
- 发明人: AISSAOUI, Hamed , CLOZEL, Martine , WELLER, Thomas , KOBERSTEIN, Ralf , SIFFERLEN, Thierry , FISCHLI, Walter
- 申请人: Actelion Pharmaceuticals Ltd.
- 申请人地址: Gewerbestrasse 16 4123 Allschwil CH
- 专利权人: Actelion Pharmaceuticals Ltd.
- 当前专利权人: Actelion Pharmaceuticals Ltd.
- 当前专利权人地址: Gewerbestrasse 16 4123 Allschwil CH
- 代理机构: Schager, Frank
- 优先权: PCT/EP03/03143 20030326
- 国际公布: WO2004085403 20041007
- 主分类号: C07D217/02
- IPC分类号: C07D217/02 ; C07D217/18 ; C07D217/20 ; C07D405/06 ; C07D217/04 ; C07D217/16 ; A61P3/04 ; A61P25/20 ; A61K31/472
摘要:
The invention relates to novel acetamide derivatives of formula (I) and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of such compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as orexin receptor antagonists.
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