发明公开
- 专利标题: PROCESS AND INTERMEDIATES FOR THE PREPARATION OF PYRROLIDINE CARBOXYLIC ACIDS
- 专利标题(中): 过程和中间产物碳氢酸吡咯烷生产
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申请号: EP04750027.7申请日: 2004-04-09
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公开(公告)号: EP1615882A2公开(公告)日: 2006-01-18
- 发明人: CVETOVICH, Raymond , CHUNG, John, Y. , AMATO, Joseph, S. , DIMICHELE, Lisa
- 申请人: Merck & Co., Inc.
- 申请人地址: 126 East Lincoln Avenue Rahway, New Jersey 07065-0907 US
- 专利权人: Merck & Co., Inc.
- 当前专利权人: Merck & Co., Inc.
- 当前专利权人地址: 126 East Lincoln Avenue Rahway, New Jersey 07065-0907 US
- 代理机构: Horgan, James Michael Frederic
- 优先权: US462795P 20030414
- 国际公布: WO2004092126 20041028
- 主分类号: C07D207/16
- IPC分类号: C07D207/16
摘要:
A novel process is provided for the preparation of pyrrolidine carboxylic acids, and the useful intermediates obtained therein. These compounds are intermediates for the synthesis of melanocortin-4 receptor (MC-4R), which are useful for the treatment of disorders such as obesity, diabetes, male sexual dysfunction, and female sexual dysfunction.
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