发明授权
- 专利标题: INTERMEDIATE COMPOUND WHICH IS USED FOR THE PREPARATION OF PIOGLITAZONE
- 专利标题(中): 中间体吡格列酮生产
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申请号: EP04731028.9申请日: 2004-05-04
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公开(公告)号: EP1623977B1公开(公告)日: 2007-11-07
- 发明人: DURAN LOPEZ, Ernesto
- 申请人: Medichem, S.A.
- 申请人地址: Fructuos Gelabert, 6-8 08970 Sant Joan Despi, Barcelona ES
- 专利权人: Medichem, S.A.
- 当前专利权人: Medichem, S.A.
- 当前专利权人地址: Fructuos Gelabert, 6-8 08970 Sant Joan Despi, Barcelona ES
- 代理机构: Elzaburu Marquez, Alberto
- 优先权: ES200301075 20030509
- 国际公布: WO2004099147 20041118
- 主分类号: C07D213/55
- IPC分类号: C07D213/55 ; C07D417/12
摘要:
The invention relates to a compound having formula (IV), which is an intermediate compound that is used for the preparation of pioglitazone. The invention also relates to a method of obtaining the novel compound (IV) from a natural product, L-tyrosine, in which the amino group, in the form of an imino-aromatic group, is protected. The invention further relates to a method of obtaining pioglitazone from the aforementioned intermediate compound.
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