发明公开
EP1625207A2 COMPOUNDS FOR TREATMENT OF INFLAMMATION, DIABETES AND RELATED DISORDERS
审中-公开
化合物炎症,糖尿病和相关疾病的治疗
- 专利标题: COMPOUNDS FOR TREATMENT OF INFLAMMATION, DIABETES AND RELATED DISORDERS
- 专利标题(中): 化合物炎症,糖尿病和相关疾病的治疗
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申请号: EP04760937.5申请日: 2004-05-07
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公开(公告)号: EP1625207A2公开(公告)日: 2006-02-15
- 发明人: NEOGI, Partha , DEY, Debedranath , FULLER, Joseph, C. , CHEN, Liang , LI, Ta-Kai
- 申请人: Theracos, Inc.
- 申请人地址: 525 Del Rey Avenue, Suite A Sunnyvale, CA 94085 US
- 专利权人: Theracos, Inc.
- 当前专利权人: Theracos, Inc.
- 当前专利权人地址: 525 Del Rey Avenue, Suite A Sunnyvale, CA 94085 US
- 代理机构: McCallum, Graeme David
- 优先权: US430677 20030507
- 国际公布: WO2004101752 20041125
- 主分类号: C12N1/00
- IPC分类号: C12N1/00
摘要:
Novel acyl urea, carbamate, thiocarbamate and related compounds are provided which are effective in inhibiting the cytokine-mediated inflammatory response in cultured cells, in ameliorating bone destruction in an animal model of arthritis and in lowering blood glucose levels in animal models of Type II diabetes mellitus. The compounds are disclosed as useful for a variety of treatments including the treatment of diabetes mellitus, insulin resistance, inflammation, inflammatory diseases, immunological diseases and cancer.
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