发明公开
EP1625777A2 OPTICAL FRACTIONATION METHODS AND APPARATUS 审中-公开
光学设备和分馏

  • 专利标题: OPTICAL FRACTIONATION METHODS AND APPARATUS
  • 专利标题(中): 光学设备和分馏
  • 申请号: EP04752357.6
    申请日: 2004-05-14
  • 公开(公告)号: EP1625777A2
    公开(公告)日: 2006-02-15
  • 发明人: GRIER, David G.
  • 申请人: UNIVERSITY OF CHICAGO
  • 申请人地址: 5801 South Ellis Avenue Chicago, IL 60637 US
  • 专利权人: UNIVERSITY OF CHICAGO
  • 当前专利权人: UNIVERSITY OF CHICAGO
  • 当前专利权人地址: 5801 South Ellis Avenue Chicago, IL 60637 US
  • 代理机构: Lawrence, John
  • 优先权: US471149P 20030516; US498868P 20030829
  • 国际公布: WO2004104551 20041202
  • 主分类号: H05H3/02
  • IPC分类号: H05H3/02
OPTICAL FRACTIONATION METHODS AND APPARATUS
摘要:
Static arrays of optical traps can be used to sort microscopic objects with exponential sensitivity to size. Such optical fractionation relies on competition between an externally applied force and the moving objects' differing affinities for optical gradient traps. In a reverse fractionation method, objects that are more strongly influenced by the traps tend to become kinetically locked in to the array and are systematically deflected back into an input flow. In a thermal ratcheting method, patterns are spaced to allow particle diffusion, thus providing the opportunity for forward or reverse movement through the patterns. Unlike other sorting techniques, optical fractionation can operate continuously and can be continuously optimized. The exponential sensitivity arises quite generally from the particle size dependence of the potential wells' apparent widths.
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