发明公开
- 专利标题: HUMANIZED ANTIBODIES TO INTERFERON ALPHA RECEPTOR-1 (IFNAR-1)
- 专利标题(中): 源化抗体与干扰素α受体-1(IFNAR-1)
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申请号: EP04750579.7申请日: 2004-04-23
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公开(公告)号: EP1631590A2公开(公告)日: 2006-03-08
- 发明人: CARDARELLI, Josephine, M. , CHEN, Tseng-hui, Timothy , KING, David , BEBBINGTON, Christopher, R. , POGUE, Sarah, Lee , CARR, Francis J. , WILLIAMS, Stephen
- 申请人: MEDAREX, INC.
- 申请人地址: 707 State Road, Suite 206 Princeton, NJ 08540-1437 US
- 专利权人: MEDAREX, INC.
- 当前专利权人: MEDAREX, INC.
- 当前专利权人地址: 707 State Road, Suite 206 Princeton, NJ 08540-1437 US
- 代理机构: Chapman, Paul Gilmour
- 优先权: US465058P 20030423
- 国际公布: WO2004094473 20041104
- 主分类号: C07K16/00
- IPC分类号: C07K16/00
摘要:
Humanized monoclonal antibodies which bind to IFNAR-1, and related antibody-based compositions and molecules, are disclosed. Also disclosed are pharmaceutical compositions comprising the humanized antibodies and therapeutic and diagnostic methods for using the humanized antibodies.
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