发明公开
- 专利标题: INDOL-DERIVATE ALS SEROTONIN-WIEDERAUFNAHME-INHIBITOREN
- 专利标题(英): Indole derivatives as serotonin reuptake inhibitors
- 专利标题(中): 吲哚衍生物血清素回收抑制剂
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申请号: EP04734515.2申请日: 2004-05-24
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公开(公告)号: EP1633741A1公开(公告)日: 2006-03-15
- 发明人: HEINRICH, Timo , BÖTTCHER, Henning , SCHIEMANN, Kai , HÖLZEMANN, Günter , VAN AMSTERDAM, Christoph , BARTOSZYK, Gerd , LEIBROCK, Joachim , SEYFRIED, Christoph
- 申请人: Merck Patent GmbH
- 申请人地址: Frankfurter Strasse 250 64293 Darmstadt DE
- 专利权人: Merck Patent GmbH
- 当前专利权人: Merck Patent GmbH
- 当前专利权人地址: Frankfurter Strasse 250 64293 Darmstadt DE
- 优先权: DE10326939 20030616
- 国际公布: WO2004113326 20041229
- 主分类号: C07D405/12
- IPC分类号: C07D405/12 ; A61K31/4045 ; A61P25/00
摘要:
Disclosed are compounds of formula (I), the use thereof for producing a medicament utilized for treating diseases related to the serotonin receptor and/or serotonin reuptake, especially for producing a medicament utilized as an anxiolytic, antidepressant, neuroleptic, and/or antihypertensive and/or for positively influencing obsessive-compulsive behavior (OCD), sleeping disorders, tardive dyskinesia, learning disorders, age-related memory defects, eating disorders such as bulimia, and/or sexual dysfunctions. The inventive compounds bond to the 5-HT1A receptor.
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