发明公开
- 专利标题： THIAZOLYLPIPERIDINE DERIVATIVES AS MTP INHIBITORS
- 专利标题（中）： THIAZOLYLPIPERIDIN衍生物作为MTP抑制剂
-
申请号： EP04735742.1申请日： 2004-06-02
-
公开(公告)号： EP1636218A1公开(公告)日： 2006-03-22
- 发明人: GUEDAT, Philippe , COLLONGES, François , DUMAS, Hervé , ORTHOLAND, Jean-Yves , DECERPRIT, Jacques , BARBANTON, Jacques , FOSTER, Richard, J. , KANE, Peter , WENDT, Bernd
- 申请人： Merck Patent GmbH
- 申请人地址： Frankfurter Strasse 250 64293 Darmstadt DE
- 专利权人： Merck Patent GmbH
- 当前专利权人： Merck Patent GmbH
- 当前专利权人地址： Frankfurter Strasse 250 64293 Darmstadt DE
- 优先权： FR0307670 20030625
- 国际公布： WO2005003128 20050113
- 主分类号： C07D417/04
- IPC分类号： C07D417/04 ; C07D417/14 ; C07D471/04 ; C07D487/04 ; C07D495/04 ; C07D491/10 ; A61K31/454 ; A61P3/04
摘要：
The present invention relates to thiazolylpiperidine derivatives of the general formula (I): in which: A represents a radical chosen from the radicals a1 and a2 below: G represents a bond or a divalent radical chosen from the groups g1, g2 and g3 below: and R1, R2, R2’, R3, R4, R5, Y and Z are as defined in the description. Application of the compounds of the formula (I) to the treatment of hypertriglyceridaemia, hypercholesterolaemia and dyslipidaemia.
公开/授权文献
- EP1636218B1 THIAZOLYLPIPERIDINE DERIVATIVES AS MTP INHIBITORS 公开/授权日：2009-03-25
信息查询
