发明公开
EP1641791A1 3-(GUANIDINOCARBONYL)HETEROCYCLE DERIVATIVES, PREPARATION PROCESS AND INTERMEDIATES OF THIS PROCESS, THEIR USE AS MEDICAMENTS, AND PHARMACEUTICAL COMPOSITIONS INCLUDING THEM
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3-（GUANIDINOCARBONYL）HETEROCYCLUSDERIVATIVE，HERSETLLUNGSVERFAHREN和用于该方法的中间产物，其使用AS药品和药物组合物含
- 专利标题： 3-(GUANIDINOCARBONYL)HETEROCYCLE DERIVATIVES, PREPARATION PROCESS AND INTERMEDIATES OF THIS PROCESS, THEIR USE AS MEDICAMENTS, AND PHARMACEUTICAL COMPOSITIONS INCLUDING THEM
- 专利标题（中）： 3-（GUANIDINOCARBONYL）HETEROCYCLUSDERIVATIVE，HERSETLLUNGSVERFAHREN和用于该方法的中间产物，其使用AS药品和药物组合物含
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申请号： EP04739421.8申请日： 2004-05-28
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公开(公告)号： EP1641791A1公开(公告)日： 2006-04-05
- 发明人: CARRY, Jean-Christophe , DOERFLINGER, Gilles, 2 avenue du Berry , GENEVOIS-BORELLA, Arielle , EVERS, Michel , LE BRUN, Alain , MARTIN, Jean-Paul , DESMAZEAU, Pascal , MIGNANI, Serge , KLEEMANN, Heinz-Werner
- 申请人： Sanofi-Aventis Deutschland GmbH
- 申请人地址： Brüningstrasse 50 65929 Frankfurt am Main DE
- 专利权人： Sanofi-Aventis Deutschland GmbH
- 当前专利权人： Sanofi-Aventis Deutschland GmbH
- 当前专利权人地址： Brüningstrasse 50 65929 Frankfurt am Main DE
- 优先权： FR0307080 20030612
- 国际公布： WO2004111048 20041223
- 主分类号： C07D471/04
- IPC分类号： C07D471/04 ; A61K31/437
摘要：
The present invention relates to the novel compounds of the formula (I) and their pharmaceutically acceptable salts. The inventive compounds are suitable, for example, as antiarrhythmic medicaments with a cardioprotective component for infarction prophylaxis and infarction treatment and for the treatment of angina pectoris. They also inhibit in a preventive manner the pathophysiologicaI processes associated with the development of ischemia-induced damage, in particular in the triggering of ischemia-induced cardiac arrhythmias and of heart failure.
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