发明公开
- 专利标题： PIPERAZINE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS
- 专利标题（中）： 哌嗪衍生物及其作为治疗剂的用途
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申请号： EP04779656.0申请日： 2004-07-29
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公开(公告)号： EP1651620A2公开(公告)日： 2006-05-03
- 发明人: SVIRIDOV, Serguei , KODUMURU, Vishnumurthy , LIU, Shifeng , ABREO, Melwyn , WINTHER, Michael, D. , GSCHWEND, Heinz, W. , KAMBOJ, Rajender , SUN, Shaoyi , HOLLADAY, Mark, W. , LI, Wenbao , TU, Chi
- 申请人： XENON PHARMACEUTICALS INC.
- 申请人地址： 3650 Gilmore Way Burnaby, British Columbia V5G 4W8 CA
- 专利权人： XENON PHARMACEUTICALS INC.
- 当前专利权人： XENON PHARMACEUTICALS INC.
- 当前专利权人地址： 3650 Gilmore Way Burnaby, British Columbia V5G 4W8 CA
- 代理机构： Weihs, Bruno Konrad
- 优先权： US491095P 20030730
- 国际公布： WO2005011657 20050210
- 主分类号： C07D239/42
- IPC分类号： C07D239/42
摘要：
Methods of treating an SCD-mediated disease or condition in a mammal, preferably a human, are disclosed, wherein the methods comprise administering to a mammal in need thereof a compound of formula (I): where G, J, L, M, x, y, W, V, R2, R3, R4, R5, R6, R7, R8, R8a, R9, R9a, R10, R10a, R11 and R11a are defined herein. Pharmaceutical compositions comprising the compounds of formula (I) are also disclosed.
公开/授权文献
- EP1651620B1 PIPERAZINE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS 公开/授权日：2011-11-09
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