发明授权
EP1651623B1 HEXAHYDRODIAZEPINONES AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES
有权
HEXAHYDRODIAZEPINONE AS二肽基肽IV用于治疗或抑制剂 预防糖尿病
- 专利标题： HEXAHYDRODIAZEPINONES AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES
- 专利标题（中）： HEXAHYDRODIAZEPINONE AS二肽基肽IV用于治疗或抑制剂 预防糖尿病
-
申请号： EP04779221.3申请日： 2004-07-27
-
公开(公告)号： EP1651623B1公开(公告)日： 2008-12-17
- 发明人: LIANG, Gui-Bai , BIFTU, Tesfaye , FENG, Danqing Dennis , WEBER, Ann, E.
- 申请人： Merck & Co., Inc.
- 申请人地址： 126 East Lincoln Avenue Rahway, New Jersey 07065-0907 US
- 专利权人： Merck & Co., Inc.
- 当前专利权人： Merck & Co., Inc.
- 当前专利权人地址： 126 East Lincoln Avenue Rahway, New Jersey 07065-0907 US
- 代理机构： Man, Jocelyn
- 优先权： US491606P 20030731
- 国际公布： WO2005011581 20050210
- 主分类号： C07D243/08
- IPC分类号： C07D243/08 ; A61P3/10 ; A61K31/551
摘要：
The present invention is directed to hexahydrodiazepinone compounds which are inhibitors of the dipeptidyl peptidase-IV enzyme ('DPP-IV inhibitors') and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.
公开/授权文献
信息查询
