发明公开
EP1661566A3 Use of beta-sheet mimetics as protease and kinase inhibitors and as inhibitors of transcription factors
失效
β-折叠片模拟物的使用作为蛋白酶抑制剂和激酶抑制剂,以及一个转录因子
- 专利标题: Use of beta-sheet mimetics as protease and kinase inhibitors and as inhibitors of transcription factors
- 专利标题(中): β-折叠片模拟物的使用作为蛋白酶抑制剂和激酶抑制剂,以及一个转录因子
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申请号: EP06000130.2申请日: 1997-08-05
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公开(公告)号: EP1661566A3公开(公告)日: 2008-04-16
- 发明人: Kahn, Michael , Ogbu, Cyprian Okwara , Qabar, Maher, Nicola , Eguchi, Masakatsu , McMillan, Michael, Kim , Kim, Hwa-Ok , Boatman, Patrick, Douglas, Jr. , Babu, Suresh , Lum, Christopher Todd , Meara, Joseph, Patrick , Ferguson, Mark D. , Urban, Jan.
- 申请人: MYRIAD GENETICS, INC.
- 申请人地址: 320 Wakara Way Salt Lake City, Utah 84108 US
- 专利权人: MYRIAD GENETICS, INC.
- 当前专利权人: MYRIAD GENETICS, INC.
- 当前专利权人地址: 320 Wakara Way Salt Lake City, Utah 84108 US
- 代理机构: Adam, Holger
- 优先权: US692420 19960805; US725073 19961002; US797915 19970210; US47067P 19970519
- 主分类号: A61K31/50
- IPC分类号: A61K31/50 ; A61K31/435 ; A61K31/415 ; A61K31/40 ; A61K38/00 ; A61K31/4035 ; A61K31/407 ; A61K31/4152 ; A61K31/428 ; A61K31/437 ; A61K31/5025 ; A61K38/04 ; A61K38/55 ; C07K1/04 ; C07K5/02 ; C07K5/06 ; C07K5/08 ; C07K5/10 ; C07K7/06
摘要:
β-sheet mimetics and methods relating to the same are disclosed. The β-sheet mimetics have utility as protease and kinase inhibitors, as well as inhibitors of transcription factors. Methods of the invention include administration of a β-sheet mimetic, or use of the same for the manufacture of a medicament for treatment of a variety of conditions associated with the targeted protease, kinase and/or transcription factor.
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