发明公开
- 专利标题: C-KIT MODULATORS AND METHODS OF USE
- 专利标题(中): C-KIT-调制器和使用方法
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申请号: EP04782473.5申请日: 2004-08-27
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公开(公告)号: EP1663204A2公开(公告)日: 2006-06-07
- 发明人: CHENG, Wei , CO, Erick, Wang , KIM, Moon, Hwan , KLEIN, Rhett, Ronald , LE, Donna, T. , LEW, Amy , NUSS, John, M. , XU, Wei , BAJJALIEH, William
- 申请人: Exelixis, Inc.
- 申请人地址: 170 Harbor Way, P.O. Box 511 South San Francisco, CA 94083-0511 US
- 专利权人: Exelixis, Inc.
- 当前专利权人: Exelixis, Inc.
- 当前专利权人地址: 170 Harbor Way, P.O. Box 511 South San Francisco, CA 94083-0511 US
- 代理机构: Grünecker, Kinkeldey, Stockmair & Schwanhäusser Anwaltssozietät
- 优先权: US499224P 20030829
- 国际公布: WO2005020921 20050310
- 主分类号: A61K31/41
- IPC分类号: A61K31/41 ; A61K31/495 ; C07D257/04 ; C07D403/04
摘要:
The present invention provides compounds for modulating protein kinase enzymatic activity for modulating cellular activities such as proliferation, differentiation, programmed cell death, migration and chemoinvasion. Even more specifically, the invention provides compounds for modulating c-Kit kinase activity and methods of treating diseases mediated by c-Kit activity utilizing the compounds and pharmaceutical compositions thereof.
公开/授权文献
- EP1663204B1 C-KIT MODULATORS AND METHODS OF USE 公开/授权日:2014-05-07
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