发明授权
- 专利标题： PENAM CRYSTAL AND PROCESS FOR PRODUCING THE SAME
- 专利标题（中）： PENAMKRISTALL和方法及其
-
申请号： EP04792516.9申请日： 2004-10-08
-
公开(公告)号： EP1671975B1公开(公告)日： 2011-02-09
- 发明人: TOKUMARU, Yoshihisa, OTSUKA CHEMICAL CO., LTD. , SHIMABAYASHI, Akihiro, OTSUKA CHEMICAL CO., LTD.
- 申请人： Otsuka Chemical Co., Ltd. , TAIHO PHARMACEUTICAL CO., LTD.
- 申请人地址： 2-27, Otedori 3-chome, Chuo-ku Osaka-shi, Osaka 540-0021 JP
- 专利权人： Otsuka Chemical Co., Ltd.,TAIHO PHARMACEUTICAL CO., LTD.
- 当前专利权人： Otsuka Chemical Co., Ltd.,TAIHO PHARMACEUTICAL CO., LTD.
- 当前专利权人地址： 2-27, Otedori 3-chome, Chuo-ku Osaka-shi, Osaka 540-0021 JP
- 代理机构： Barz, Peter
- 优先权： JP2003352723 20031010
- 国际公布： WO2005035538 20050421
- 主分类号： C07D499/00
- IPC分类号： C07D499/00
摘要：
Novel 2α-methyl-2β-[(1,2,3-triazol-1-yl)methyl]penam-3α-carboxylic acid benzhydryl ester (TMPB)-acetone crystals for use in producing 2α-methyl-2β-[(1,2,3-triazol-1-yl)methyl]penam-3α-carboxylic acid 1,1-dioxide benzhydryl ester (TAZB); a process for producing TMPB-acetone crystals which comprises (A) the step of concentrating an organic solvent solution containing TMPB, (B) the step of dissolving the resultant concentrate in acetone, and (C) the step of crystallizing TMPB-acetone crystals from the acetone solution obtained; and a process for producing TAZB which comprises the step of reacting TMPB-acetone crystals with an oxidizing agent.
公开/授权文献
- EP1671975A1 PENAM CRYSTAL AND PROCESS FOR PRODUCING THE SAME 公开/授权日：2006-06-21
信息查询
