发明公开
EP1680085A4 A NOVEL CATIONIC LIPOPOLYMER AS A BIOCOMPATIBLE GENE DELIVERY AGENT
审中-公开
NEW阳离子脂质聚合物作为生物相容性GENZUFUHRMITTEL
- 专利标题： A NOVEL CATIONIC LIPOPOLYMER AS A BIOCOMPATIBLE GENE DELIVERY AGENT
- 专利标题（中）： NEW阳离子脂质聚合物作为生物相容性GENZUFUHRMITTEL
-
申请号： EP03796920申请日： 2003-12-10
-
公开(公告)号： EP1680085A4公开(公告)日： 2006-10-18
- 发明人: MAHATO RAM I , HAN SANG-OH , FURGESON DARIN Y , ANWER KHURSHEED
- 申请人： EXPRESSION GENETICS INC
- 专利权人： EXPRESSION GENETICS INC
- 当前专利权人： EXPRESSION GENETICS INC
- 优先权： US71710903 2003-11-19
- 主分类号： A61K9/127
- IPC分类号： A61K9/127 ; A61K47/48 ; A61K48/00 ; C08G73/02
摘要：
A biodegradable cationic lipopolymer comprising a polyethylenimine (PEI), a lipid, and a biocompatible hydrophilic polymer, wherein 1) the lipid and the biocompatible hydrophilic polymer are directly linked to the PEI backbone or 2) the lipid is linked to the PEI backbone through the biocompatible hydrophilic polymer. The cationic lipopolymers of the present invention can be used for delivery of a nucleic acid or any anionic bioactive agent to various organs and tissues after local or systemic administration.
信息查询
