发明公开
- 专利标题： MACROCYCLIC LACTAMS AND PHARMACEUTICAL USE THEREOF
- 专利标题（中）： 大环内酰胺类和它们的药物用途
-
申请号： EP04797621.2申请日： 2004-11-04
-
公开(公告)号： EP1682521A1公开(公告)日： 2006-07-26
- 发明人: AUBERSON, Yves , BETSCHART, Claudia , GLATTHAR, Ralf , LAUMEN, Kurt , MACHAUER, Rainer , TINTELNOT-BLOMLEY, Marina , TROXLER, Thomas, J. , VEENSTRA, Siem, Jacob
- 申请人： Novartis AG , Novartis Pharma GmbH
- 申请人地址： Lichtstrasse 35 4056 Basel CH
- 专利权人： Novartis AG,Novartis Pharma GmbH
- 当前专利权人： Novartis AG,Novartis Pharma GmbH
- 当前专利权人地址： Lichtstrasse 35 4056 Basel CH
- 代理机构： Crawley, Patrick Edward
- 优先权： GB0325830 20031105
- 国际公布： WO2005049585 20050602
- 主分类号： C07D245/02
- IPC分类号： C07D245/02 ; C07D281/00 ; C07D255/02 ; A61K31/33 ; A61P25/00
摘要：
The present invention relates to novel macrocyclic compounds of the formula (I) wherein R1, R2, R3, U, V, W, X, Y, Z and n are as defined in the specification, the number of ring atoms included in the macrocyclic ring being 14, 15, 16 or 17, in free base form or in acid addition salt form, to their preparation, to their use as pharmaceuticals and to pharmaceutical compositions comprising them.
信息查询
