发明授权
EP1697399B1 A HUMAN CYTOTOXIC T-LYMPHOCYTE EPITOPE AND ITS AGONIST EPITOPE FROM THE NON-VARIABLE NUMBER OF TANDEM REPEAT SEQUENCE OF MUC-1
有权
表位人细胞毒性T淋巴细胞及其AGONISTENEPITOP FROM MUC-1的串联重复序列的非可变NUMBER
- 专利标题： A HUMAN CYTOTOXIC T-LYMPHOCYTE EPITOPE AND ITS AGONIST EPITOPE FROM THE NON-VARIABLE NUMBER OF TANDEM REPEAT SEQUENCE OF MUC-1
- 专利标题（中）： 表位人细胞毒性T淋巴细胞及其AGONISTENEPITOP FROM MUC-1的串联重复序列的非可变NUMBER
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申请号： EP04814140.2申请日： 2004-12-10
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公开(公告)号： EP1697399B1公开(公告)日： 2016-11-23
- 发明人: SCHLOM, Jeffrey , TSANG, Kwong-Yok
- 申请人： GOVERNMENT OF THE UNITED STATES OF AMERICA, as repr. by THE SECR. OF THE DEPT. OF HEALTH AND HUMAN SERVICES AND HIS SUCCESSORS
- 申请人地址： Washington, DC 20231 US
- 专利权人： GOVERNMENT OF THE UNITED STATES OF AMERICA, as repr. by THE SECR. OF THE DEPT. OF HEALTH AND HUMAN SERVICES AND HIS SUCCESSORS
- 当前专利权人： GOVERNMENT OF THE UNITED STATES OF AMERICA, as repr. by THE SECR. OF THE DEPT. OF HEALTH AND HUMAN SERVICES AND HIS SUCCESSORS
- 当前专利权人地址： Washington, DC 20231 US
- 代理机构： Davies, Jonathan Mark
- 优先权： US529329P 20031212
- 国际公布： WO2005058937 20050630
- 主分类号： G01N33/53
- IPC分类号： G01N33/53 ; G01N33/567 ; C07K16/18 ; C07K7/64
摘要：
Novel MUC-1 epitopes outside the VNTR region are identified. In addition, the first agonist epitope of MUC-1 is described. The employment of agonist epitopes in peptide, protein and vector-based vaccine may well aid in the development of effective vaccines for a range of human cancers.
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