发明公开
EP1697542A2 COMPOSITIONS AND METHODS OF USING APOPTOSIS SIGNALING KINASE RELATED KINASE (ASKRK)
审中-公开
组合物之使用ASKRK方法（细胞凋亡信号激酶相关激酶）
- 专利标题： COMPOSITIONS AND METHODS OF USING APOPTOSIS SIGNALING KINASE RELATED KINASE (ASKRK)
- 专利标题（中）： 组合物之使用ASKRK方法（细胞凋亡信号激酶相关激酶）
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申请号： EP04810311.3申请日： 2004-11-03
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公开(公告)号： EP1697542A2公开(公告)日： 2006-09-06
- 发明人: JOHNSON, Jeffrey, D. , ZHOU, Yun-Ping , MARLEN, Kimberly
- 申请人： METABOLEX, INC.
- 申请人地址： 3876 Bay Center Place Hayward, CA 94545 US
- 专利权人： METABOLEX, INC.
- 当前专利权人： METABOLEX, INC.
- 当前专利权人地址： 3876 Bay Center Place Hayward, CA 94545 US
- 代理机构： Brasnett, Adrian Hugh
- 优先权： US517477P 20031104
- 国际公布： WO2005044993 20050519
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68 ; C07H21/04 ; C12N9/12 ; C12N5/06 ; C12P21/02
摘要：
The invention provides apoptosis signaling kinase related kinase (ASKRK) nucleic acid and polypeptide sequences and methods of using such sequences to identify modulators of ASKRK. Such modulators can be used for the treatment of diabetes or for delaying the onset of diabetes. The invention also provides methods of diagnosing diabetes or pre-diabetes and methods of making a prognosis based on the detection of ASKRK nucleic acids and proteins.
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