发明授权
EP1701956B1 PYRROLO[2,3-B]PYRIDINE DERIVATIVES ACTIVE AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM
有权
吡咯并[2,3-B]吡啶衍生物作为激酶抑制剂WORK,METHOD FOR THEIR和药物组合物含
- 专利标题: PYRROLO[2,3-B]PYRIDINE DERIVATIVES ACTIVE AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM
- 专利标题(中): 吡咯并[2,3-B]吡啶衍生物作为激酶抑制剂WORK,METHOD FOR THEIR和药物组合物含
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申请号: EP04816308.3申请日: 2004-12-23
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公开(公告)号: EP1701956B1公开(公告)日: 2010-02-24
- 发明人: SALOM, Barbara , D'ANELLO, Matteo , BRASCA, Maria, Gabriella , GIORDANO, Patrizia , MARTINA, Katia , ANGELUCCI, Francesco , BROOKFIELD, Frederick, Arthur , TRIGG, William, John, Evotec OAI , BOYD, Edward, Andrew , LARARD, Jonathan, Anthony
- 申请人: Pfizer Italia S.r.l.
- 申请人地址: Via SS 156 Km. 50 04100 Latina IT
- 专利权人: Pfizer Italia S.r.l.
- 当前专利权人: Pfizer Italia S.r.l.
- 当前专利权人地址: Via SS 156 Km. 50 04100 Latina IT
- 代理机构: Modiano, Micaela Nadia
- 优先权: GB0330043 20031224
- 国际公布: WO2005063746 20050714
- 主分类号: C07D471/04
- IPC分类号: C07D471/04 ; A61K31/437
摘要:
Compounds which are pyrrolo[2,3-b]pyridine derivatives or pharmaceutically acceptable salts thereof, their preparation process and pharmaceutical compositions comprising them are disclosed; these compounds are useful in the treatment of diseases caused by and/or associated with an altered protein kinase activity such as cancer, cell proliferative disorders, Alzheimer's disease, viral infections, auto-immune diseases and neurodegenerative disorders; also disclosed is a process under SPS conditions for preparing the compounds of the invention and chemical libraries comprising a plurality of them.
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