发明公开
EP1711490A1 NOVEL P-GLYCOPROTEIN INHIBITOR, METHOD FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME
审中-公开
新的P-GLYCOPROTEININHIBITOR，对于其方法和药物组合物包含此
- 专利标题： NOVEL P-GLYCOPROTEIN INHIBITOR, METHOD FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME
- 专利标题（中）： 新的P-GLYCOPROTEININHIBITOR，对于其方法和药物组合物包含此
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申请号： EP04774781.1申请日： 2004-10-07
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公开(公告)号： EP1711490A1公开(公告)日： 2006-10-18
- 发明人: CHA, Mi Young, Cheongsolmaeul Halla Apt. , BANG, Keuk Chan, Mansujugong Apt. , AHN, Young Gil, Sangrokmaeul Life Apt. , KIM, Maeng Sup , LEE, Gwan Sun
- 申请人： Hanmi Pharm. Co., Ltd.
- 申请人地址： 893-5, Hajeori, Paltanmeon, Hwaseonggun Kyungki-do 445-910 KR
- 专利权人： Hanmi Pharm. Co., Ltd.
- 当前专利权人： Hanmi Pharm. Co., Ltd.
- 当前专利权人地址： 893-5, Hajeori, Paltanmeon, Hwaseonggun Kyungki-do 445-910 KR
- 代理机构： Grünecker, Kinkeldey, Stockmair & Schwanhäusser Anwaltssozietät
- 优先权： KR2003069803 20031008
- 国际公布： WO2005033101 20050414
- 主分类号： C07D405/12
- IPC分类号： C07D405/12
摘要：
A p-glycoprotein inhibitor of Formula 1 is capable of effectively preventing the development of multi-drug resistance directed to an anticancer agent in cancer cells, and greatly enhances the bioavailability of the drug, such as paclitaxel, which is not readily absorbed when orally administered.
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