发明公开
- 专利标题: BIPHENYL COMPOUNDS USEFUL AS MUSCARINIC RECEPTOR ANTAGONISTS
- 专利标题(中): 联苯基化合物可用作麦考酚酸受体拮抗剂
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申请号: EP05730718.3申请日: 2005-03-10
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公开(公告)号: EP1723115A1公开(公告)日: 2006-11-22
- 发明人: MAMMEN, Mathai , JI, Yu-Hua , MU, YongQi
- 申请人: Theravance, Inc.
- 申请人地址: 901 Gateway Boulevard South San Francisco, CA 94080 US
- 专利权人: Theravance, Inc.
- 当前专利权人: Theravance, Inc.
- 当前专利权人地址: 901 Gateway Boulevard South San Francisco, CA 94080 US
- 代理机构: Hay, Martin Alexander
- 优先权: US552264P 20040311
- 国际公布: WO2005087737 20050922
- 主分类号: C07D211/62
- IPC分类号: C07D211/62 ; C07D409/14 ; A61K31/445 ; A61K31/4535 ; A61P11/00
摘要:
This invention provides compounds of formula (I), wherein a, b, c, d, m, n, p, s, t, Ar1, R1, R2, R3, R4, R6, R7, R8, and W are as defined in the specification. The compounds of formula I are muscarinic receptor antagonists. The invention also provides pharmaceutical compositions containing such compounds, processes and intermediates for preparing such compounds and methods of using such compounds to treat pulmonary disorders.
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