Body fluid sampling device comprising a skin-piercing element (1) having a collection zone (9) for receiving body fluid, and the device further comprising a fluid receiving means (10) remote spaced apart from said collection zone so that body fluid in said collection zone will not contact the fluid receiving means initially. Said collection zone takes up a very small volume of body fluid of about 10 to 500 nl in a very short time period of less than 0,5 s. Said fluid receiving means may have a test zone for performing an analytical reaction. Fluid sample from said collection zone is automatically or manually transported to said fluid receiving means to contact said fluid with said test zone.