发明授权
EP1725544B1 3-[4-HETEROCYCLYL-1,2,3-TRIAZOL-1-YL]-N-ARYL-BENZAMIDES AS INHIBITORS OF THE CYTOKINES PRODUCTION FOR THE TREATMENT OF CHRONIC INFLAMMATORY DISEASES
有权
3- [4 - 杂环基-1,2,3-三唑-1-基] -N- ARYLBENZAMIDE AS CYTOKINENPRODUKTION治疗慢性炎性疾病的治疗抑制剂
- 专利标题： 3-[4-HETEROCYCLYL-1,2,3-TRIAZOL-1-YL]-N-ARYL-BENZAMIDES AS INHIBITORS OF THE CYTOKINES PRODUCTION FOR THE TREATMENT OF CHRONIC INFLAMMATORY DISEASES
- 专利标题（中）： 3- [4 - 杂环基-1,2,3-三唑-1-基] -N- ARYLBENZAMIDE AS CYTOKINENPRODUKTION治疗慢性炎性疾病的治疗抑制剂
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申请号： EP05724523.5申请日： 2005-03-04
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公开(公告)号： EP1725544B1公开(公告)日： 2009-05-27
- 发明人: COGAN, Derek; Boehringer Ingelheim Pharm., Inc. , HAO, Ming-Hong, Boehringer Ingelheim Pharm., Inc. , KAMHI, Victor Marc , MILLER, Craig A., Boehringer Ingelheim Pharm. Inc. , NETHERTON, M. R., Boehringer Ingelheim Pharm. Inc. , SWINAMER, Alan D., Boehringer Ingelheim Pharm. Inc
- 申请人： Boehringer Ingelheim Pharmaceuticals Inc.
- 申请人地址： 900 Ridgebury Road, P.O. Box 368 Ridgefield, Connecticut 06877-0368 US
- 专利权人： Boehringer Ingelheim Pharmaceuticals Inc.
- 当前专利权人： Boehringer Ingelheim Pharmaceuticals Inc.
- 当前专利权人地址： 900 Ridgebury Road, P.O. Box 368 Ridgefield, Connecticut 06877-0368 US
- 代理机构： Hammann, Heinz
- 优先权： US551445P 20040309
- 国际公布： WO2005090333 20050929
- 主分类号： C07D403/04
- IPC分类号： C07D403/04 ; C07D401/14 ; C07D401/04 ; C07D405/04 ; C07D417/04 ; A61K31/4192 ; A61P29/00
摘要：
Disclosed compounds of formula (I), which inhibit production of cytokines involved in inflammatory processes and are thus useful for treating diseases and pathological conditions involving inflammation such as chronic inflammatory disease. Also disclosed are processes for preparing these compounds and pharmaceutical compositions comprising these compounds.
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