The invention relates to a method and an arrangement for portion cutting of food items, especially meat products, into pieces of predetermined shape, such as quadratic meat pieces, where the method comprises the following steps: feeding of the items in a first cutting device in a first feeding direction, in which device the items are cut into strips in a cutting unit, transfer of the strips from the first cutting device to at least one additional cutting device with another feeding direction different from that of the first feeding direction, and cutting in at least the one additional cutting device, in which by a cutting unit the strips are cut into pieces of predetermined shape, such as quadratic meat pieces. Furthermore, there is disclosed the use of a cutting device in an arrangement according to the invention.