发明授权
EP1742952B1 (POLY) AMINOACETAMIDE DERIVATIVES OF EPIPODOPHYLLOTOXIN, THEIR PROCESS OF PREPARATION AND THEIR APPLICATIONS IN THERAPEUTICS AS ANTICANCER AGENTS
有权
(POLY)AMINOACETAMIDDERIVATE表鬼臼毒素,其制备方法及其应用在治疗中用作抗恶性肿瘤药
- 专利标题: (POLY) AMINOACETAMIDE DERIVATIVES OF EPIPODOPHYLLOTOXIN, THEIR PROCESS OF PREPARATION AND THEIR APPLICATIONS IN THERAPEUTICS AS ANTICANCER AGENTS
- 专利标题(中): (POLY)AMINOACETAMIDDERIVATE表鬼臼毒素,其制备方法及其应用在治疗中用作抗恶性肿瘤药
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申请号: EP05734896.3申请日: 2005-04-14
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公开(公告)号: EP1742952B1公开(公告)日: 2008-07-30
- 发明人: IMBERT, Thierry , GUMINSKI, Yves , BARRET, Jean-Marc , KRUCZINSKI, Anna
- 申请人: PIERRE FABRE MEDICAMENT
- 申请人地址: 45, Place Abel Gance 92100 Boulogne-Billancourt FR
- 专利权人: PIERRE FABRE MEDICAMENT
- 当前专利权人: PIERRE FABRE MEDICAMENT
- 当前专利权人地址: 45, Place Abel Gance 92100 Boulogne-Billancourt FR
- 代理机构: Ahner, Francis
- 优先权: FR0404053 20040416
- 国际公布: WO2005100363 20051027
- 主分类号: C07D493/04
- IPC分类号: C07D493/04 ; A61K31/343 ; A61P35/00
摘要:
The present invention relates to novel podophyllotoxin derivatives substituted in the 4-position by a substituted (poly)aminoalkylaminoacetamide chain, to their process of preparation and to their use as medicament as anticancer agents.
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