发明公开
EP1756051A1 HISTAMINE H3 RECEPTOR AGENTS, PREPARATION AND THERAPEUTIC USES
有权
组胺H3受体活性的化合物，它们的制备和治疗用途
- 专利标题： HISTAMINE H3 RECEPTOR AGENTS, PREPARATION AND THERAPEUTIC USES
- 专利标题（中）： 组胺H3受体活性的化合物，它们的制备和治疗用途
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申请号： EP05754884.4申请日： 2005-05-24
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公开(公告)号： EP1756051A1公开(公告)日： 2007-02-28
- 发明人: BEAVERS, Lisa, Selsam , GADSKI, Robert, Alan , JESUDASON, Cynthia, Darshini , PICKARD, Richard, Todd , STEVENS, Freddie, Craig
- 申请人： ELI LILLY AND COMPANY
- 申请人地址： Lilly Corporate Center Indianapolis, Indiana 46285 US
- 专利权人： ELI LILLY AND COMPANY
- 当前专利权人： ELI LILLY AND COMPANY
- 当前专利权人地址： Lilly Corporate Center Indianapolis, Indiana 46285 US
- 代理机构： Suarez-Miles, Ana Sanchiz
- 优先权： US576421P 20040602
- 国际公布： WO2005121080 20051222
- 主分类号： C07D207/09
- IPC分类号： C07D207/09 ; C07D401/12 ; C07D403/12 ; A61K31/4025 ; A61P3/04 ; A61P25/00
摘要：
The present invention discloses novel compounds of Formula I or pharmaceutically acceptable salts thereof which have histamine-H3 receptor antagonist or inverse agonist activity, as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising compounds of Formula I as well as methods of using these compositions to treat obesity, cognitive deficiencies, narcolepsy, and other histamine H3 receptor-related diseases.
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