发明公开
EP1756173A2 METHOD OF PREPARING PROPIONIC ACID-TERMINATED POLYMERS
审中-公开
用于生产聚合物PROPIONSÄURETERMINIERTEN
- 专利标题： METHOD OF PREPARING PROPIONIC ACID-TERMINATED POLYMERS
- 专利标题（中）： 用于生产聚合物PROPIONSÄURETERMINIERTEN
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申请号： EP05711695.6申请日： 2005-01-21
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公开(公告)号： EP1756173A2公开(公告)日： 2007-02-28
- 发明人: KOZLOWSKI, Antoni , MCMANUS, Samuel, P.
- 申请人： Nektar Therapeutics Al, Corporation
- 申请人地址： 490 Discovery Drive Huntsville, AL 35806 US
- 专利权人： Nektar Therapeutics Al, Corporation
- 当前专利权人： Nektar Therapeutics Al, Corporation
- 当前专利权人地址： 490 Discovery Drive Huntsville, AL 35806 US
- 代理机构： Baldock, Sharon Claire
- 优先权： US538006P 20040121
- 国际公布： WO2005070973 20050804
- 主分类号： C08F8/00
- IPC分类号： C08F8/00
摘要：
The invention provides methods for preparing polymers bearing a terminal propionic acid. The method involves first reacting a water soluble and non-peptidic polymer comprising at least one hydroxyl group with a tertiary alkyl acrylate in the presence of a catalyst to form a propionic acid ester of the polymer, wherein the polymer has a weight average molecular weight of at least about 10,000 Da; and then treating the propionic acid ester of the polymer with a strong acid to form a propionic acid of the polymer.
公开/授权文献
- EP1756173B1 METHOD OF PREPARING PROPIONIC ACID-TERMINATED POLYMERS 公开/授权日：2019-04-03
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