发明公开
- 专利标题: COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS
- 专利标题(中): 化合物和组合物作为蛋白激酶抑制剂
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申请号: EP05759571.2申请日: 2005-06-09
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公开(公告)号: EP1758892A1公开(公告)日: 2007-03-07
- 发明人: REN, Pingda , WANG, Xia , ZHANG, Guobao , DING, Qiang , YOU, Shuli , ZHANG, Qiong , CHOPIUK, Greg , ALBAUGH, Pamela A. , SIM, Taebo , GRAY, Nathanael Schiander
- 申请人: IRM LLC
- 申请人地址: Hurst Holme 12 Trott Road Hamilton HM 11 BM
- 专利权人: IRM LLC
- 当前专利权人: IRM LLC
- 当前专利权人地址: Hurst Holme 12 Trott Road Hamilton HM 11 BM
- 代理机构: Roth, Peter Richard
- 优先权: US578491P 20040610
- 国际公布: WO2005123719 20051229
- 主分类号: C07D403/04
- IPC分类号: C07D403/04 ; A61K31/4178
摘要:
The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of the Abl, BCR-Abl, PDGF-R, trkB, c-SRC, BMX, FGFR3, b-RAF, SGK, Tie2, Lck, JNK2 2, MKK4, c-RAF, MKK6, SAPK2 and SAPK2 kinases.
公开/授权文献
- EP1758892B1 COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS 公开/授权日:2012-10-17
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