发明公开
- 专利标题： TREATMENT OF NON ALCOHOLIC STEATOTIC HEPATITIS (NASH)
- 专利标题（中）： 非酒精STEATOTISCHER肝炎治疗（NASH）
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申请号： EP05753069.3申请日： 2005-06-20
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公开(公告)号： EP1761273A1公开(公告)日： 2007-03-14
- 发明人: VAN DEVENTER, Sander, Jan, Hendrik
- 申请人： ACADEMISCH ZIEKENHUIS BIJ DE UNIVERSITEIT VAN AMSTERDAM , Amsterdam Molecular Therapeutics B.V. (AMT)
- 申请人地址： Meibergdreef 9 1105 AZ Amsterdam NL
- 专利权人： ACADEMISCH ZIEKENHUIS BIJ DE UNIVERSITEIT VAN AMSTERDAM,Amsterdam Molecular Therapeutics B.V. (AMT)
- 当前专利权人： ACADEMISCH ZIEKENHUIS BIJ DE UNIVERSITEIT VAN AMSTERDAM,Amsterdam Molecular Therapeutics B.V. (AMT)
- 当前专利权人地址： Meibergdreef 9 1105 AZ Amsterdam NL
- 代理机构： Swinkels, Bart Willem
- 优先权： US580903P 20040621
- 国际公布： WO2005123117 20051229
- 主分类号： A61K38/46
- IPC分类号： A61K38/46 ; A61K48/00 ; A61P1/16
摘要：
The present invention relates to a method for treating nonalcoholic steatotic hepatitis (NASH) in a subject by administering an effective amount of a lipoprotein lipase (LPL) therapeutic to the subject. The LPL therapeutic is advantageoulsy a S447X protein or a derivative or variant thereof, or a nucleic acid encoding such a protein. The LPL therapeutic may be used in a gene therapy vector.
公开/授权文献
- EP1761273B1 TREATMENT OF NON ALCOHOLIC STEATOTIC HEPATITIS (NASH) 公开/授权日：2008-05-14
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