发明公开
- 专利标题： MITOTIC KINESIN INHIBITORS
- 专利标题（中）： 抑制剂有丝分裂驱动蛋白
-
申请号： EP05786157.7申请日： 2005-06-27
-
公开(公告)号： EP1765830A1公开(公告)日： 2007-03-28
- 发明人: BERGMAN, Jeffrey, M. , COLEMAN, Paul, J. , FRALEY, Mark, E. , GARBACCIO, Robert, M. , HARTMAN, George, D. , LI, Chunze , NEILSON, Lou Anne , OLSON, Christy, M. , TASBER, Edward, S.
- 申请人： Merck & Co., Inc.
- 申请人地址： 126 East Lincoln Avenue Rahway, New Jersey 07065-0907 US
- 专利权人： Merck & Co., Inc.
- 当前专利权人： Merck & Co., Inc.
- 当前专利权人地址： 126 East Lincoln Avenue Rahway, New Jersey 07065-0907 US
- 代理机构： Hussain, Deeba
- 优先权： US584808P 20040701; US600901P 20040812
- 国际公布： WO2006007491 20060119
- 主分类号： C07D498/04
- IPC分类号： C07D498/04 ; C07D519/00 ; A61K31/5383 ; A61P35/00
摘要：
The present invention relates to tricyclic pyrazoles according to Formula (I) that are useful for treating cellular proliferative diseases, for treating disorders associated with KSP kinesin activity, and for inhibiting KSP kinesin. The invention also relates to compositions which comprise these compounds, and methods of using them to treat cancer in mammals.
公开/授权文献
- EP1765830B1 MITOTIC KINESIN INHIBITORS 公开/授权日：2010-09-22
信息查询
