发明公开
EP1768982A2 PYROLO [2,3-D] PYRIMIDINES THAT MODULATE ACK1 AND LCK ACTIVITY
审中-公开
Pyrolo [2,3-D]嘧啶类，所述ACK1-及LCK活性而调节
- 专利标题： PYROLO [2,3-D] PYRIMIDINES THAT MODULATE ACK1 AND LCK ACTIVITY
- 专利标题（中）： Pyrolo [2,3-D]嘧啶类，所述ACK1-及LCK活性而调节
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申请号： EP05768263.5申请日： 2005-06-29
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公开(公告)号： EP1768982A2公开(公告)日： 2007-04-04
- 发明人: FARTHING, Christopher N. , FAULDER, Paul , FRENKEL, Alexander David , HARRISON, Martin James , JIAO, Xianyun , KAYSER, Frank , KOPECKY, David J. , LIU, Jinqian , LIVELY, Sarah E. , SHARMA, Rajiv , SHUTTLEWORTH, Stephen Joseph
- 申请人： Amgen Inc.
- 申请人地址： One Amgen Center Drive Thousand Oaks, CA 91320-1799 US
- 专利权人： Amgen Inc.
- 当前专利权人： Amgen Inc.
- 当前专利权人地址： One Amgen Center Drive Thousand Oaks, CA 91320-1799 US
- 代理机构： Woods, Geoffrey Corlett
- 优先权： US583682P 20040629
- 国际公布： WO2006004703 20060112
- 主分类号： C07D487/00
- IPC分类号： C07D487/00 ; A61K31/519 ; A61P35/00
摘要：
Compounds that modulate the action of ACK1 and LCK, and related compositions methods for treating ACK1- and LCK-mediated diseases are described. In one aspect, the compounds have the general structure: where the values of the substituents are provided herein.
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