发明授权
EP1773310B9 ALPHA, BETA-UNSATURATED SULFONES, SULFOXIDES, SULFONIMIDES, SULFINIMIDES, ACYLSULFONAMIDES AND ACYLSULFINAMIDES AND THERAPEUTIC USES THEREOF
有权
α,β-不饱和砜SULFONOXIDE,磺酰亚胺SULFINIMIDE,酰基磺酰胺和ACYLSULFINAMIDE和治疗使用了
- 专利标题: ALPHA, BETA-UNSATURATED SULFONES, SULFOXIDES, SULFONIMIDES, SULFINIMIDES, ACYLSULFONAMIDES AND ACYLSULFINAMIDES AND THERAPEUTIC USES THEREOF
- 专利标题(中): α,β-不饱和砜SULFONOXIDE,磺酰亚胺SULFINIMIDE,酰基磺酰胺和ACYLSULFINAMIDE和治疗使用了
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申请号: EP05812220.1申请日: 2005-06-23
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公开(公告)号: EP1773310B9公开(公告)日: 2012-04-25
- 发明人: REDDY, Premkumar, E. , REDDY, Ramana, M. V.
- 申请人: Temple University - Of The Commonwealth System of Higher Education
- 申请人地址: Broad Street and Montgomery Avenue Philadelphia, PA 19122 US
- 专利权人: Temple University - Of The Commonwealth System of Higher Education
- 当前专利权人: Temple University - Of The Commonwealth System of Higher Education
- 当前专利权人地址: Broad Street and Montgomery Avenue Philadelphia, PA 19122 US
- 代理机构: Ouzman, Beverley Nicola Claire
- 优先权: US583009P 20040624
- 国际公布: WO2006025924 20060309
- 主分类号: A61K31/18
- IPC分类号: A61K31/18 ; A61K31/4439 ; C07C317/10 ; C07D333/18 ; C07D333/22
摘要:
α,β-Unsaturated sulfones, sulfoxides, sulfonimides, sulfinimides, acylsulfonamides and acylsulfinamides of Formula I: wherein R1 R2, M1 M2, L, E1, E2, Q1, Q2 and n are as defined herein, are useful as anti-angiogenesis agents, as agents for treatment of age related senile dementia, and as antiproliferative agents including, for example, as anticancer agents.
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