发明公开
EP1778860A1 METHODS FOR DETERMINING THE POTENCY, SPECIFICITY, AND TOXICITY OF HEMATOPOIETIC PROSTAGLANDIN D2 SYNTHASE
有权
确定方法的有效性,特异性和造血前列腺素D2合酶的毒性
- 专利标题: METHODS FOR DETERMINING THE POTENCY, SPECIFICITY, AND TOXICITY OF HEMATOPOIETIC PROSTAGLANDIN D2 SYNTHASE
- 专利标题(中): 确定方法的有效性,特异性和造血前列腺素D2合酶的毒性
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申请号: EP05781699.3申请日: 2005-07-28
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公开(公告)号: EP1778860A1公开(公告)日: 2007-05-02
- 发明人: CAO, Yang , SABOL, Jeffrey, S. , AYERS, Stephen
- 申请人: Aventis Pharmaceuticals Inc.
- 申请人地址: 300 Somerset Corporate Boulevard Bridgewater, New Jersey 08807-0800 US
- 专利权人: Aventis Pharmaceuticals Inc.
- 当前专利权人: Aventis Pharmaceuticals Inc.
- 当前专利权人地址: 300 Somerset Corporate Boulevard Bridgewater, New Jersey 08807-0800 US
- 代理机构: Bouvet, Philippe
- 优先权: US592501P 20040730
- 国际公布: WO2006015195 20060209
- 主分类号: C12Q1/533
- IPC分类号: C12Q1/533 ; G01N33/573 ; G01N33/88
摘要:
The present invention relates to a novel and useful method for assaying compounds and agents for their ability to decrease or inhibit the activity of hematopoietic prostaglandin D2 synthase (hPGDS). Specifically, the present invention relates to assays for measuring the potency, specificity and toxicity of hPGDS inhibitors.
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