发明公开
EP1789018A1 ENHANCED DELIVERY OF DRUG COMPOSITIONS TO TREAT LIFE THREATENING INFECTIONS
审中-公开
对于生命的威胁治疗感染的组合物药物的提高，交货期
- 专利标题： ENHANCED DELIVERY OF DRUG COMPOSITIONS TO TREAT LIFE THREATENING INFECTIONS
- 专利标题（中）： 对于生命的威胁治疗感染的组合物药物的提高，交货期
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申请号： EP05804416.5申请日： 2005-08-26
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公开(公告)号： EP1789018A1公开(公告)日： 2007-05-30
- 发明人: HITT, James, E. , ROGERS, True, L. , GILLESPIE, Ian, B. , SCHERZER, Brian, D. , GARCIA, Paula, C. , BECK, Nicholas, S. , TUCKER, Christopher, J. , YOUNG, Timothy, J. , HAYES, David, A. , WILLIAMS, Robert, O., III , JOHNSTON, Keith, P. , MCCONVILLE, Jason, T. , PETERS, Jay, I. , TALBERT, Robert , BURGESS, David
- 申请人： THE DOW CHEMICAL COMPANY , Board of Regents, The University of Texas System
- 申请人地址： 2030 Dow Center Midland, MI 48674 US
- 专利权人： THE DOW CHEMICAL COMPANY,Board of Regents, The University of Texas System
- 当前专利权人： THE DOW CHEMICAL COMPANY,Board of Regents, The University of Texas System
- 当前专利权人地址： 2030 Dow Center Midland, MI 48674 US
- 代理机构： Raynor, John
- 优先权： US605179P 20040827
- 国际公布： WO2006026502 20060309
- 主分类号： A61K9/12
- IPC分类号： A61K9/12 ; A61K31/496
摘要：
Inhalable compositions are described. The inhalable compositions comprise one or more respirable aggregates, the respirable aggregates comprising one or more poorly water soluble active agents, wherein at least one of the active agents reaches a maximum lung concentration (Cmax) of at least about 0.25 μg/gram of lung tissue and remains at such concentration for a period of at least one hour after being delivered to the lung. Methods for making such compositions and methods for using such compositions are also disclosed.
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