发明公开
EP1790365A1 DIRECT HEMOPERFUSION ADSORBER PACKED WITH ADSORBENT HAVING WATER INSOLUBLE MICROPARTICLE REMOVED THEREFROM, AND METHOD OF OBTAINING DIRECT HEMOPERFUSION ADSORBENT HAVING WATER INSOLUBLE MICROPARTICLE REMOVED THEREFROM
有权
DIRECTHÄMOPERFUSIONSADSORBER，吸附剂挤满了文章远水不溶性微粒和方法保持直接HÄMOPERFUSIONSADSORBENS被添加的文章远水不溶性微粒
- 专利标题： DIRECT HEMOPERFUSION ADSORBER PACKED WITH ADSORBENT HAVING WATER INSOLUBLE MICROPARTICLE REMOVED THEREFROM, AND METHOD OF OBTAINING DIRECT HEMOPERFUSION ADSORBENT HAVING WATER INSOLUBLE MICROPARTICLE REMOVED THEREFROM
- 专利标题（中）： DIRECTHÄMOPERFUSIONSADSORBER，吸附剂挤满了文章远水不溶性微粒和方法保持直接HÄMOPERFUSIONSADSORBENS被添加的文章远水不溶性微粒
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申请号： EP05766271.0申请日： 2005-07-20
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公开(公告)号： EP1790365A1公开(公告)日： 2007-05-30
- 发明人: FUJITA, Koji , NAKATANI, Masaru , KOBAYASHI, Akira , NISHIMOTO, Takehiro
- 申请人： Kaneka Corporation
- 申请人地址： 2-4, Nakanoshima 3-chome Kita-ku Osaka-shi, Osaka 530-8288 JP
- 专利权人： Kaneka Corporation
- 当前专利权人： Kaneka Corporation
- 当前专利权人地址： 2-4, Nakanoshima 3-chome Kita-ku Osaka-shi, Osaka 530-8288 JP
- 代理机构： Wiedemann, Peter
- 优先权： JP2004215411 20040723
- 国际公布： WO2006009179 20060126
- 主分类号： A61M1/36
- IPC分类号： A61M1/36 ; A61L33/00 ; B01J20/28
摘要：
The present invention has its object to provide a direct hemoperfusion adsorber packed with an adsorbent made by using a water-insoluble carrier having a relatively readily available particle size distribution, with water-insoluble microparticles having been removed therefrom, without needing any special granulation apparatus or coating apparatus, and method of obtaining a direct hemoperfusion adsorbent having water-insoluble microparticles removed therefrom.
Now, a direct hemoperfusion adsorber has been obtained that is packed with an adsorbent having a number average particle diameter of not smaller than 300 µm but not larger than 600 µm, with the coefficient of variance in particle diameter distribution being not lower than 10% but not higher than 20%, and having water-insoluble microparticles removed therefrom to a safe level, without the loss of the adsorbent, by using a water-insoluble microparticle-removing-mesh such that the ratio of the mesh opening size for removing water-insoluble microparticles to the mesh opening size of the adsorber is not lower than 1.3 but not higher than 1.5.
Now, a direct hemoperfusion adsorber has been obtained that is packed with an adsorbent having a number average particle diameter of not smaller than 300 µm but not larger than 600 µm, with the coefficient of variance in particle diameter distribution being not lower than 10% but not higher than 20%, and having water-insoluble microparticles removed therefrom to a safe level, without the loss of the adsorbent, by using a water-insoluble microparticle-removing-mesh such that the ratio of the mesh opening size for removing water-insoluble microparticles to the mesh opening size of the adsorber is not lower than 1.3 but not higher than 1.5.
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