发明公开
EP1790664A1 Monoclonal antibodies against claudin-18 for treatment of cancer
审中-公开
对蛋白 - 18单克隆抗体治疗癌症
- 专利标题: Monoclonal antibodies against claudin-18 for treatment of cancer
- 专利标题(中): 对蛋白 - 18单克隆抗体治疗癌症
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申请号: EP05025657.7申请日: 2005-11-24
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公开(公告)号: EP1790664A1公开(公告)日: 2007-05-30
- 发明人: Sahin, Ugur , Türeci, Özlem , Fritz, Stefan , Uherek, Christoph , Brandenburg, Gunda , Geppert, Harald-Gerhard
- 申请人: Ganymed Pharmaceuticals AG , Johannes Gutenberg-Universität Mainz, vertreten durch den Präsidenten
- 申请人地址: Freiligrathstr. 12 55131 Mainz DE
- 专利权人: Ganymed Pharmaceuticals AG,Johannes Gutenberg-Universität Mainz, vertreten durch den Präsidenten
- 当前专利权人: Ganymed Pharmaceuticals AG,Johannes Gutenberg-Universität Mainz, vertreten durch den Präsidenten
- 当前专利权人地址: Freiligrathstr. 12 55131 Mainz DE
- 代理机构: Schnappauf, Georg
- 主分类号: C07K16/30
- IPC分类号: C07K16/30 ; A61K39/395 ; A61P35/00 ; C12N5/12 ; A61K47/48
摘要:
The present invention provides antibodies useful as therapeutics for treating and/or preventing diseases associated with cells expressing CLD18, including tumor-related diseases such as gastric cancer, esophageal cancer, pancreatic cancer, lung cancer, ovarian cancer, colon cancer, hepatic cancer, head-neck cancer, and cancer of the gallbladder.
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