发明公开
EP1794190A2 IMMUNOGENIC T-HELPER EPITOPES FROM HUMAN TUMOUR ANTIGENS AND IMMUNOTHERAPEUTIC METHODS USING SAID EPITOPES
有权
人类肿瘤抗原的免疫原性T辅助表位和它们在免疫治疗方法
- 专利标题： IMMUNOGENIC T-HELPER EPITOPES FROM HUMAN TUMOUR ANTIGENS AND IMMUNOTHERAPEUTIC METHODS USING SAID EPITOPES
- 专利标题（中）： 人类肿瘤抗原的免疫原性T辅助表位和它们在免疫治疗方法
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申请号： EP05778354.0申请日： 2005-09-09
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公开(公告)号： EP1794190A2公开(公告)日： 2007-06-13
- 发明人: RAMMENSEE, Hans-Georg , WEINSCHENK, Toni , DENGJEL, Jörn
- 申请人： Immatics Biotechnologies GmbH
- 申请人地址： Paul-Ehrlich-Str. 15 72076 Tübingen DE
- 专利权人： Immatics Biotechnologies GmbH
- 当前专利权人： Immatics Biotechnologies GmbH
- 当前专利权人地址： Paul-Ehrlich-Str. 15 72076 Tübingen DE
- 代理机构： Krauss, Jan
- 优先权： EP04023546 20041002
- 国际公布： WO2006037421 20060413
- 主分类号： C07K14/47
- IPC分类号： C07K14/47
摘要：
The present invention relates to immunotherapeutic methods, and molecules and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer, in particular renal cancer. The present invention furthermore relates to tumour-associated T-helper cell peptide epitopes, alone or in combination with other tumour-associated peptides, that serve as active pharmaceutical ingredients of vaccine compositions which stimulate anti-tumour immune responses. In particular, the present invention relates to 338 novel peptide sequences derived from HLA class II molecules of human tumour cell lines which can be used in vaccine compositions for eliciting anti-tumour immune responses.
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