发明公开
EP1796663A2 TRICYCLIC HETEROARYL PIPERAZINES, PYRROLIDINES AND AZETIDINES AS SEROTONIN RECEPTOR MODULATORS
有权
三环杂芳哌嗪，吡咯烷和氮杂环丁烷血清素受体调节剂
- 专利标题： TRICYCLIC HETEROARYL PIPERAZINES, PYRROLIDINES AND AZETIDINES AS SEROTONIN RECEPTOR MODULATORS
- 专利标题（中）： 三环杂芳哌嗪，吡咯烷和氮杂环丁烷血清素受体调节剂
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申请号： EP05794345.8申请日： 2005-09-01
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公开(公告)号： EP1796663A2公开(公告)日： 2007-06-20
- 发明人: BENNANI, Youssef, L. , BOM, David C. , ROBARGE, Michael, J.
- 申请人： Athersys, Inc.
- 申请人地址： 3201 Carnegie Avenue Cleveland, OH 44115-2634 US
- 专利权人： Athersys, Inc.
- 当前专利权人： Athersys, Inc.
- 当前专利权人地址： 3201 Carnegie Avenue Cleveland, OH 44115-2634 US
- 代理机构： Modiano, Micaela Nadia
- 优先权： US607142P 20040903
- 国际公布： WO2006028961 20060316
- 主分类号： A61K31/407
- IPC分类号： A61K31/407 ; C07D495/02
摘要：
The present invention generally relates to a series of compounds, to pharmaceutical compositions containing the compounds, and to use the compounds and compositions as therapeutic agents. More specifically, compounds of the present invention are hexahydroazepinoindole and octahydroazepinoindole compounds. These compounds are serotonin receptor (5-HT) ligands and are useful for treating diseases, disorders, and conditions wherein modulation of the activity of serotonin receptors (5-HT) is desired (e.g. anxiety, depression and obesity).
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