发明授权
- 专利标题: CGRP RECEPTOR ANTAGONISTS
- 专利标题(中): CGRP受体拮抗剂
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申请号: EP05803913.2申请日: 2005-10-12
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公开(公告)号: EP1802372B1公开(公告)日: 2011-05-04
- 发明人: PAONE, Daniel, V. , SHAW, Anthony, W. , POTTEIGER, Craig, M.
- 申请人: Merck Sharp & Dohme Corp.
- 申请人地址: 126 East Lincoln Avenue Rahway, NJ 07065 US
- 专利权人: Merck Sharp & Dohme Corp.
- 当前专利权人: Merck Sharp & Dohme Corp.
- 当前专利权人地址: 126 East Lincoln Avenue Rahway, NJ 07065 US
- 代理机构: Buchan, Gavin MacNicol
- 优先权: US618715P 20041014
- 国际公布: WO2006044449 20060427
- 主分类号: A61P25/00
- IPC分类号: A61P25/00 ; A61K31/55 ; C07D401/00 ; C07D487/00
摘要:
Compounds of Formula (I) and Formula (II) (where variables R1, R2, R4, A, B, W, X, Y and Z are as defined herein) useful as antagonists of CGRP receptors and useful in the treatment or prevention of diseases in which the CGRP is involved, such as headache, migraine and cluster headache. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.
公开/授权文献
- EP1802372A2 CGRP RECEPTOR ANTAGONISTS 公开/授权日:2007-07-04
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