发明公开
- 专利标题: FIBRONECTIN III DOMAIN AS LEPTIN RECEPTOR ANTAGONISTS
- 专利标题(中): 纤连蛋白III域瘦素受体拮抗剂
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申请号: EP05813344.8申请日: 2005-11-16
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公开(公告)号: EP1812038A1公开(公告)日: 2007-08-01
- 发明人: TAVERNIER, Jan , ZABEAU, Lennart
- 申请人: VIB vzw , UNIVERSITEIT GENT
- 申请人地址: Rijvisschestraat 120 9052 Zwijnaarde BE
- 专利权人: VIB vzw,UNIVERSITEIT GENT
- 当前专利权人: VIB vzw,UNIVERSITEIT GENT
- 当前专利权人地址: Rijvisschestraat 120 9052 Zwijnaarde BE
- 优先权: EP04105864 20041118
- 国际公布: WO2006053883 20060526
- 主分类号: A61K38/16
- IPC分类号: A61K38/16 ; A61K38/22 ; A61K39/395
摘要:
The invention relates to a new type of leptin receptor antagonist, which is able to prevent leptin signaling without preventing the binding of leptin to the leptin binding domain. More specifically, the invention relates to the use of a part of the leptin receptor to prevent the leptin- dependent activation of the receptor, and by this the leptin induced signaling.
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