An endoscope (10) comprising a first light source (14) for illuminating biological tissue with light, a first detector (30) for detecting macroscopic images from the tissue by reflected light and fluorescent light induced in the tissue, a second light source (60) for illuminating the tissue with light, a confocal microscopic waveguide (50) for supplying light from the second light source (60) to the tissue and for supplying microscopic fluorescent images of the tissue and a second detector (68) for detecting the microscopic fluorescent images of the tissue and a second detector (68) for detecting the microscopic fluorescent images from the confocal microscopic waveguide (50).