发明授权
EP1824489B1 STEREOISOMERICALLY ENRICHED 3-AMINOCARBONYL BICYCLOHEPTENE PYRIMIDINEDIAMINE COMPOUNDS AND THEIR USES
有权
富含立体异构体-3-氨基羰基 - 二环嘧啶化合物及其用途
- 专利标题： STEREOISOMERICALLY ENRICHED 3-AMINOCARBONYL BICYCLOHEPTENE PYRIMIDINEDIAMINE COMPOUNDS AND THEIR USES
- 专利标题（中）： 富含立体异构体-3-氨基羰基 - 二环嘧啶化合物及其用途
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申请号： EP05844183.3申请日： 2005-11-15
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公开(公告)号： EP1824489B1公开(公告)日： 2011-01-05
- 发明人: ARGADE, Ankush , SINGH, Rajinder , LI, Hui
- 申请人： Rigel Pharmaceuticals, Inc.
- 申请人地址： 1180 Veterans Boulevard South San Francisco, CA 94080 US
- 专利权人： Rigel Pharmaceuticals, Inc.
- 当前专利权人： Rigel Pharmaceuticals, Inc.
- 当前专利权人地址： 1180 Veterans Boulevard South San Francisco, CA 94080 US
- 代理机构： Sexton, Jane Helen
- 优先权： US628199P 20041115
- 国际公布： WO2006055561 20060526
- 主分类号： C07D239/48
- IPC分类号： C07D239/48 ; C07D413/12
摘要：
The present invention provides stereoisomers and stereoisomeric mixtures of 3-aminocarbonyl-bicycloheptene-2,4-pyrimidinediamine compounds having antiproliferative activity, compositions comprising the compounds and methods of using the compounds to inhibit cellular proliferation and to treat proliferate diseases such as tumorigenic cancers.
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