发明公开
- 专利标题: MUTANT PROTEIN HAVING PEPTIDE-PRODUCTION ACTIVITY
- 专利标题(中): 用肽生产活动蛋白突变体
-
申请号: EP05820283申请日: 2005-12-20
-
公开(公告)号: EP1829968A4公开(公告)日: 2008-09-10
- 发明人: ABE ISAO , TAKESHITA RIE , HARA SEIICHI , SUZUKI SONOKO , YOKOZEKI KENZO , SUGIYAMA MASAKAZU , SUZUKI SHUNICHI , WATANABE KUNIHIKO , SHIMBA NOBUHISA , NAKAMURA TAKEFUMI , TAGAMI UNO , KODAMA YUYA , ONOYE HIROMI , YUUJI REIKO , SUZUKI EIICHIRO , KASHIWAGI TATSUKI , XU NINGCHUN , KAI YUKO
- 申请人: AJINOMOTO KK
- 专利权人: AJINOMOTO KK
- 当前专利权人: AJINOMOTO KK
- 优先权: JP2004368503 2004-12-20
- 主分类号: C12N15/09
- IPC分类号: C12N15/09 ; C12N9/00 ; C12P13/00 ; C12P21/02
摘要:
Disclosed is an excellent peptide-producing protein. Also disclosed is a process for producing a peptide with high efficiency, or the like. The process comprises reacting an amine component with a carboxy component in the presence of at least one of the following proteins (I) and (II) to produce a peptide: (I) a mutant protein comprising an amino acid sequence having one or more of the mutations shown in mutation types 1 to 68, 239 to 290 and 324 to 377 in the amino acid sequence depicted in SEQ ID NO: 2; and (II) a mutant protein comprising an amino acid sequence having one or more of the mutations shown in mutation types L1 to L335 and M1 to M642 in the amino acid sequence depicted in SEQ ID NO: 208.
信息查询
IPC分类: