A data handling system for handling multiple datasets is provided with an access module for accessing datasets of several categories and a connection module to link datasets in the respective categories. From a region of interest in one anatomical image a link is provided to the corresponding region of interest in other types of images and/or other types of data, such as a time intensity curve for that region of interest. Also the propagation of the region of interest in one image, such as an anatomical image, through a temporal succession of images may constitute links through an image series.