发明公开
EP1836203A2 HETEROARYL SUBSTITUTED QUINOLIN-4-YLAMINE ANALOGUES
审中-公开
HETEROARYL-SUBSTITUIERTE CHINOLIN-4-YLAMIN-ANALOGA
- 专利标题： HETEROARYL SUBSTITUTED QUINOLIN-4-YLAMINE ANALOGUES
- 专利标题（中）： HETEROARYL-SUBSTITUIERTE CHINOLIN-4-YLAMIN-ANALOGA
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申请号： EP06718423.4申请日： 2006-01-13
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公开(公告)号： EP1836203A2公开(公告)日： 2007-09-26
- 发明人: CALDWELL, Timothy M. , CHENARD, Bertrand , HODGETTS, Kevin
- 申请人： NEUROGEN CORPORATION
- 申请人地址： 35 N.E. Industrial Road Branford, CT 06405 US
- 专利权人： NEUROGEN CORPORATION
- 当前专利权人： NEUROGEN CORPORATION
- 当前专利权人地址： 35 N.E. Industrial Road Branford, CT 06405 US
- 代理机构： Forstmeyer, Dietmar
- 优先权： US644503P 20050114
- 国际公布： WO2006076646 20060720
- 主分类号： C07D471/02
- IPC分类号： C07D471/02 ; C07D215/38 ; C07D215/44 ; C07D401/00 ; C07D403/00 ; C07D409/00 ; C07D239/02 ; C07D471/00 ; C07D487/00 ; C07D491/00 ; C07D495/00 ; C07D497/00 ; A01N43/58 ; A01N43/60 ; A01N43/54 ; A01N43/42 ; A61K31/50 ; A61K31/45 ; A61K31/501 ; A61K31/505 ; A61K31/47
摘要：
Heteroaryl substituted quinolin-4-ylamine analogues of Formula (I) are provided. Such compounds are ligands that may be used to modulate specific receptor activity in vivo or in vitro, and are particularly useful in the treatment of conditions associated with pathological receptor activation in humans, domesticated companion animals and livestock animals. Pharmaceutical compositions and methods for using such compounds to treat such disorders are provided, as are methods for using such ligands for receptor localization studies.
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