发明公开
- 专利标题: COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS
- 专利标题(中): 作为蛋白激酶抑制剂的化合物和组合物
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申请号: EP06733803.8申请日: 2006-01-19
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公开(公告)号: EP1841431A2公开(公告)日: 2007-10-10
- 发明人: SIM, Taebo , GRAY, Nathanael Schiander , LEE, Hyun Soo , LIU, Yi , REN, Pingda , YOU, Shuli , ZHANG, Qiong , DING, Qiang , WANG, Xia , JIANG, Songchun , ALBAUGH, Pamela A.
- 申请人: IRM, LLC
- 申请人地址: Hurst Holme 12 Trott Road Hamilton, HM 11 BM
- 专利权人: IRM, LLC
- 当前专利权人: IRM, LLC
- 当前专利权人地址: Hurst Holme 12 Trott Road Hamilton, HM 11 BM
- 代理机构: Kiddle, Simon John
- 优先权: US647606P 20050126
- 国际公布: WO2006081172 20060803
- 主分类号: A61K31/5377
- IPC分类号: A61K31/5377
摘要:
The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of the Abl, Bcr-Abl, FGFR3, PDGFRβ and b-Raf kinases.
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