发明公开
- 专利标题： MRI CONTRAST AGENTS FOR DIAGNOSIS AND PROGNOSIS OF TUMORS
- 专利标题（中）： MRI造影剂诊断和预后肿瘤
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申请号： EP06701708.7申请日： 2006-01-31
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公开(公告)号： EP1848466A2公开(公告)日： 2007-10-31
- 发明人: DEGANI, Hadassa , MILSTEIN, David
- 申请人： YEDA RESEARCH AND DEVELOPMENT CO., LTD.
- 申请人地址： The Weizmann Institute of Science P.O. Box 95 76100 Rehovot IL
- 专利权人： YEDA RESEARCH AND DEVELOPMENT CO., LTD.
- 当前专利权人： YEDA RESEARCH AND DEVELOPMENT CO., LTD.
- 当前专利权人地址： The Weizmann Institute of Science P.O. Box 95 76100 Rehovot IL
- 代理机构： Vossius & Partner
- 优先权： US647821P 20050131
- 国际公布： WO2006080022 20060803
- 主分类号： A61K49/10
- IPC分类号： A61K49/10
摘要：
The invention relates to bifunctional conjugates comprising a receptor ligand moiety and a metal binding moiety and complexes thereof with paramagnetic lanthanide or transition metals, and to the use of the metal complexes as contrast agents in magnetic resonance imaging (MRI) of tumors and other abnormalities.
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